Visa Information
This position comes with a certificate of sponsorship for eligible international candidates. However, applicants must verify their visa eligibility directly with the employer. Even with sponsorship offered, you must ensure you meet all UK immigration requirements before applying.
Job Overview
Guy’s and St Thomas’ NHS Foundation Trust is offering an exciting opportunity for a Paediatric Clinical Research Nurse to join their dynamic team. This position is based at the Paediatric Genetics Research unit at St. Thomas’ Hospital in London and provides a unique chance to work with children who have rare genetic diseases.
The successful candidate will play a key role in coordinating and delivering genetic portfolio research studies, including observational, phase 2 and phase 3 clinical trials involving investigational medicinal product studies (CTIMPs). The role focuses on developing new therapies for skeletal disorders through groundbreaking clinical trials using precision medications.
Role Details
As a Paediatric Research Nurse, you will be responsible for the holistic nursing care of children and young people and their families participating in clinical trials. You’ll contribute to the assessment and management of care pathways for patients in clinical studies and act as an ambassador for promoting research utilization and best practice.
The normal working hours are Monday to Friday, 9am-5pm, though flexibility may be required to accommodate patient visits and assessments outside of these hours when necessary. This is a fixed-term position for 12 months on a full-time basis.
Essential Qualifications
Applicants must have extensive experience of working within an acute paediatric ward environment as a qualified nurse with previous acute NHS experience. You must be registered with the Nursing and Midwifery Council (NMC) as a Nurse (Child).
You must hold a current paediatric immediate life support qualification and demonstrate evidence of ongoing continuing professional development. These qualifications are essential for ensuring you can provide the highest standard of care in this specialized clinical research environment.
Desirable Qualifications
While not required, having experience in staff management and development would be advantageous for this role. Additionally, knowledge of research governance and regulations, including ICH/GCP and EU Directives, is considered desirable.
GCP (Good Clinical Practice) accreditation is also desirable, as it demonstrates your understanding of the ethical and legal constraints of clinical research. These additional qualifications would enhance your ability to contribute effectively to the research team.
Essential Experience
Candidates must demonstrate understanding of resource management, health and safety, clinical risk and quality issues. You should also have a solid understanding of professional and current issues in children’s nursing, along with knowledge of clinical governance and improvement agenda.
Previous experience of handling clinical incidents and complaints is essential, as is experience of research and audit. These competencies ensure you can maintain high standards of care while navigating the complexities of clinical research environments.
About the Employer
Guy’s and St Thomas’ NHS Foundation Trust comprises five of the UK’s best known hospitals – Guy’s, St Thomas’, Evelina London Children’s Hospital, Royal Brompton and Harefield – as well as community services in Lambeth and Southwark. The trust has a long history of high quality care, clinical excellence, research and innovation.
Dr Melita Irving leads the paediatric genetics team, having helped establish whole exome sequencing as a diagnostic genetic test and setting up dedicated multidisciplinary clinics in skeletal dysplasia and other genetic conditions. As part of King’s Health Partners, the trust is one of England’s eight academic health sciences centres.
Research Portfolio
The trials portfolio covers various commercial and non-commercial trials focusing on skeletal dysplasia conditions and biologic treatments. This represents a unique opportunity to be at the forefront of medical innovation in rare genetic diseases affecting children.
The team prides itself on adopting holistic care for patients, advocating for children and their families, and helping them navigate the complex and innovative research space. This approach ensures that both clinical excellence and patient welfare remain at the heart of all research activities.
Compensation and Benefits
The position offers a competitive salary ranging from £46,419 to £55,046 per annum, inclusive of HCA (pro rata). This reflects the specialized nature of the role and the importance of clinical research within the NHS.
In addition to the salary, the trust provides a comprehensive benefits package including access to the NHS pension scheme, generous annual leave, and opportunities for professional development. The fixed-term nature of the position (12 months) may also provide opportunities for extension or permanent placement based on performance and organizational needs.
Work Environment
The Paediatric Genetics Research unit is located at St. Thomas’ Hospital in London (SE1 7EH), one of the UK’s leading teaching hospitals. The hospital provides state-of-the facilities and a supportive environment for both clinical care and research activities.
Working within this academic health sciences centre means you’ll be part of a multidisciplinary team of healthcare professionals, researchers, and academics who are dedicated to improving outcomes for children with rare genetic diseases. The collaborative environment fosters innovation and professional growth.
Professional Development
This position offers unparalleled opportunities for professional development in a unique medical field. You’ll have the chance to learn new skills in genetic research, participate in groundbreaking clinical trials, and contribute to the advancement of precision medicine for skeletal disorders.
The trust is committed to the ongoing development of its staff and provides various opportunities for training, education, and career progression. As part of your role, you’ll be encouraged to maintain your continuing professional development and contribute to the research and audit activities of the team.
Team Culture
The research team is described as energetic and dedicated to helping infants and young people with rare diseases. The collaborative approach ensures that all team members work together to provide the best possible care and advance medical knowledge in this specialized field.
The team operates with a strong emphasis on holistic care, recognizing that supporting children with rare genetic diseases requires addressing not only their medical needs but also the needs of their families. This patient-centered approach is central to the team’s philosophy and practice.
Application Requirements
All applicants must have current UK professional registration. For overseas applicants, this means you’ll need to obtain NMC registration if not already registered in the UK. The trust welcomes applications from international candidates who require skilled worker sponsorship.
The post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975, meaning a Disclosure and Barring Service (DBS) check will be required. Additionally, skilled worker applicants must present criminal record certificates from any country where they have resided for 12 months or more in the past 10 years.
How to Apply
To apply for this position, please visit the NHS Jobs website and search for reference number 196-RD404E. The application deadline is 12 January 2026. For questions about the job, contact Amy Day (Research Manager) at amy.day25@nhs.net.
International applicants should follow these steps: 1) Verify your visa eligibility with the employer, 2) Ensure you have all required documentation including proof of qualifications and professional registration, 3) Prepare a comprehensive CV and cover letter highlighting your relevant experience, and 4) Be prepared to discuss your immigration status during the interview process.
Equal Opportunities
Guy’s and St Thomas’ NHS Foundation Trust is an equal opportunities employer and welcomes applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation, or age. The trust is committed to creating a diverse and inclusive workplace.
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The trust holds several accreditations including Age Positive, CQC Good rating, and IIP Gold status, demonstrating their commitment to staff development and wellbeing. These accreditations reflect the trust’s dedication to maintaining high standards of employment practice and creating a positive working environment for all staff.
Contact Information
For further information about this position or the application process, please contact Amy Day, Research Manager, at amy.day25@nhs.net. The trust’s main careers website can be found at https://www.guysandstthomas.nhs.uk/careers/careers.aspx where you can find more information about working with the trust.
Please note that all applications must be submitted through the NHS Jobs website. The trust is unable to accept applications via email or other channels. For the best chance of success, ensure your application clearly demonstrates how you meet the essential and desirable criteria outlined in the person specification.